Mediterranean fever: genes can cause fever

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Family Mediterranean fever: genes can trigger febrile episodes

Children often have a fever in infancy. If this is still the case at primary school age and later, a genetic disease can be the trigger - familial Mediterranean fever. This disease mainly occurs in children of Arabic, Armenian, Greek, Turkish or Israeli origin.

How does familial Mediterranean fever differ from other febrile illnesses? Experts believe that eight to twelve febrile illnesses are normal in infancy. If there are frequent episodes of fever even at primary school age and later for one to three days with temperatures above 38.5 degrees Celsius, an hereditary illness could be the trigger. Ulrich Fegeler from the professional association of pediatricians in Cologne advises: "If parents observe repeated episodes of fever, they should report it to their pediatrician." Write down fever-related symptoms. " In children, such febrile episodes can be familial Mediterranean fever. However, this usually only occurs in children of Arabic, Turkish, Greek, Armenian or Israeli origin.

Symptoms of familial Mediterranean fever The symptoms of familial Mediterranean fever include flare-ups with high fever and sometimes severe pain, which are caused by inflammation of the peritoneum, pectoral skin and the inner skin of the joint capsules. Family Mediterranean fever is triggered by a malfunction of the immune system, which causes the body to react with infections for no apparent reason. These do not occur at certain time intervals. There can even be years between batches.

People who suffer from familial Mediterranean fever have an increased risk of death. This is mainly due to a possible amyloidosis, the main complication in addition to renal failure. During an acute episode there is a lot of amyloid in the patient's blood, which can be deposited in the organs and cause serious damage there. (ag)

Image: Maria Lanznaster /

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Video: Fever and Infection -- Shuchi Pandya, MD


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