Blood type affects risk of heart attack

Blood type affects risk of heart attack

According to a study, blood group influences the risk of developing a heart attack

So far, an unhealthy lifestyle has primarily been a risk factor for a heart attack. Diabetes, high blood pressure and family history, as well as factors that can be influenced, including high-fat diet, obesity, lack of exercise and nicotine, have an impact on the development of coronary artery disease, such as the blood group, according to American scientists. Accordingly, people with AB blood type are at greatest risk of suffering a heart attack.

How the blood group affects coronary heart disease is still largely unknown. In the specialist journal "Arteriosclerosis, Thrombosis and Vascular Biology", the researchers report that the blood group AB also has an increased tendency to inflammation.

Increased risk of heart attack with blood group AB
A team of American scientists analyzed the data from around 90,000 people regarding the relationship between heart attacks and blood type. The investigation showed that carriers of the rare blood group AB have the highest risk of constipation of the coronary arteries, while blood group 0 has a 23 percent lower risk. People with blood groups A and B were also at five and eleven percent more at risk than blood group 0.

How these differences come about is still unclear. However, there were certain blood group-specific differences, such as susceptibility to inflammation and cholesterol levels, the scientists report. "While a person cannot change their blood type, our results could help us better understand who is at higher risk of a heart attack in the future," said Lu Qi of the Harvard School of Public Health in Boston, director of the study If you know your own risk based on your blood type, you can prevent the disease accordingly, including an unhealthy diet and lots of exercise.

Context of heart attack and blood group examined in 90,000 people
As the scientists write, they evaluated the health and lifestyle data of nearly 90,000 people, including 62,073 women and 27,428 men. Participants were between 30 and 75 years old when the study started and were followed for over 20 years. The data were provided by the US "Nurses Health Study" and the "Health Professionals" study.

During the evaluation, the scientists examined the number of heart attacks within the individual blood groups and analyzed the differences. They also took into account the lifestyle of the study participants such as diet, smoking, age and weight. Accordingly, blood group 0 carries the lowest risk of coronary heart disease. According to the German Red Cross, 41 percent of the population in Germany have this blood type. According to researchers, blood groups A and B are at greater risk of five and eleven percent, however, but people with the rare blood group AB are at greatest risk. Their risk of constipation of the coronary arteries is therefore 23 percent higher than that of blood group 0. Only five percent of Germans have blood group AB.

Blood group 0 with the lowest risk of heart attack
So far, the scientists have not been able to explain why there are differences in the blood group-specific risk of heart attacks. However, it had been noticed that blood group A was often found to have a slightly elevated level of so-called low-density cholesterol (LDL cholesterol), which promoted arteriosclerosis. In addition, an increased tendency to inflammation was observed in blood group AB. Blood group 0 with the lowest risk of heart attacks also contains more of a substance that facilitates blood flow and prevents clumping. "The biology of the blood groups is very complicated, so several processes could be involved," Qi reports. Further studies are needed "to determine the biological cause of the differences." If the different dangers are confirmed, it could be helpful to know his blood type. "Because then it could be that people with different blood types react very differently, for example, to a change in diet," said the study leader.

Heart attack is one of the leading causes of death in industrialized countries
Heart attacks are still one of the leading causes of death in industrialized countries. Around 250,000 people suffer a heart attack in Germany every year, of which around one in four die from the direct consequences. Due to circulatory disorders, which are usually caused by blood clots in a constriction of the coronary arteries, parts of the heart muscle die. This is an acute emergency situation in which the first few minutes are of crucial importance. Only with the fastest possible cardiopulmonary resuscitation can death or severe damage from an oxygen deficiency in the brain be prevented.

Research has shown that about half of those who died of an infarction died within the first 15 minutes. The prognosis after a heart attack essentially depends on whether favorable risk factors continue to exist and how much myocardial tissue is affected. (ag)

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Author and source information

Video: How Your Blood Type Protects and Hurts You (October 2020).