Microbiologists: Combat antibiotic resistance

Microbiologists: Combat antibiotic resistance

Avoid spread of antibiotic-resistant pathogens, but how?

Pathogens resistant to antibiotics are a growing problem in clinics across Germany. The multi-resistant germs are called MRSA, VRSA or ESBL and are a threat that should not be underestimated for hospital patients. The cause of the development is the careless or improper use of antibiotics and the lack of compliance with hygiene regulations, the experts reported at the annual congress of the German Society for Hygiene and Microbiology (DGHM) in Hamburg that started on Sunday.

As part of the 64th DGHM annual conference, several lectures yesterday explicitly addressed the increased spread of multi-resistant pathogens and possible countermeasures. As the conference president Professor Martin Aepfelbacher from the Institute for Medical Microbiology, Virology and Hygiene at the University Medical Center Hamburg-Eppendorf previously reported, "almost all known antibiotic-resistant hospital germs are on the rise worldwide and also in Germany." The pathogens can trigger dangerous infections against that no medication is available. In order to minimize the further increase in resistance, improved hygiene measures and restrictions on the use of antibiotics are absolutely necessary, the experts reported at the DGHM annual conference. Monitoring should also be set up that immediately records the use of antibiotics and new resistance. Infection protection in the clinics must also be improved and the development of new effective antibiotics must be promoted.

Infections with multi-resistant hospital germs Around 3.5 percent of hospital patients contract an infection with multi-resistant hospital germs, the experts reported at the congress of the German Society for Hygiene and Microbiology based on the data from the Robert Koch Institute in Berlin. Such infections are a significant health risk for the already weakened patients. The increasing number of antibiotic-resistant clinical germs include, for example, methicillin-resistant Staphylococcus aureus (MRSA) bacteria, but also vancomycin-resistant Staphylococcus aureus (VRSA) strains and Extended Spectrum Beta-Lactamase (ESBL) producing pathogens from the genus Escherichia . coli) and adhesive. Since no new antibiotics are available in the medium term, the experts are very concerned about the current development. However, effective antibiotics have been developed against the MRSA bacteria known for more than 50 years in the past twelve years. However, the treatment of the patients is usually difficult and lengthy.

Lack of treatment options for infections with multidrug-resistant pathogens As the President of the DGHM Congress, Professor Martin Aepfelbacher, explained, the threat of antibiotic-resistant germs can only be countered by early diagnosis, intensive hygiene management and extensive measures to prevent infections. In the opinion of the experts, the so-called ESBL germs, which occur as intestinal pathogens in the intestine (E. coli and Klebsielles), are a threat that should not be underestimated, since there are currently no treatment options for such infections. The risk to the benefit of the patient can only be minimized here by improving prevention. A more careful use of antibiotics is also urgently needed.

Use of antibiotics in animal husbandry favors the development of resistant pathogens The fatal consequences of improper use of antibiotics can be seen not only in the clinics, but also in animal husbandry. Here the drugs are often used in a prohibited manner to promote growth, which favors the development of multi-resistant germs. According to the Robert Koch Institute (RKI), 82 percent of pigs and 86 percent of people working in pig farming in Germany are fattened with multi-resistant germs in the fattening farms. Not only the use of antibiotics in clinics, but also their use in animal husbandry, should therefore be significantly reduced. (fp)

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Antibiotic resistance is increasing rapidly
Resistant germs due to antibiotic animal husbandry

Author and source information

Video: Mechanism of Antibiotic Resistance (September 2020).